AMH (Anti-Müllerian hormone) is a hormone that is secreted by specialised granulosa cells in ovarian follicles. It is produced by small follicles with a diameter of less than 4 millimetre in a woman's ovaries, and its production is highest when the egg is still maturing. Once it has crossed that size, AMH production decreases and later stops. Biologically, younger women have more small follicles resulting in a higher ovarian reserve and hence, AMH. Contrarily, older women have a lesser number of small follicles resulting in low production of AMH. Follicles continue to decline in number with age, hence by the time a woman reaches menopause, there are no viable eggs left in the ovaries leading to a complete drop in AMH level.
AMH levels are used as a measure of a woman’s fertility potential, especially in advancing age. Increased levels might indicate syndromes such as polycystic ovary syndrome (PCOS), whereas reduced levels normally show a lack of ovarian reserve. Such reduction in AMH creates an issue for conception, particularly at the older age, suggesting decreased fertility. Women with low AMH will more likely need higher doses of medicine to stimulate egg growth and may not respond as well to fertility treatments by IVF.
Low AMH levels, as actress Rubina Dilaik highlighted in her recent podcast, can pose hurdles to natural conception. Lower AMH levels reflect a decreased ovarian reserve, which means that there are fewer eggs available for fertilisation, and natural conception becomes difficult, especially in women with values less than 1.5. Additionally, those with levels of 1.5 to 4.5 usually have a normal reserve, while higher levels of 4.5 or more may indicate polycystic ovary syndrome (PCOS).
Low AMH levels in women aged 20-25 may lead to conception through natural means with quite minimal fertility evaluations or medical interventions required. Low AMH levels in women aged 35 and above constitute a serious issue as they often struggle to get pregnant naturally and the baby is at greater risk of chromosomal abnormalities. Research reflects a significant drop in the viable eggs in women above the age of 35.
Monitoring of AMH levels in regular blood tests at particular intervals within the menstrual cycle is a fundamental tool in detecting low ovarian reserves at an early stage, providing valuable information for family planning considerations. Acknowledging the significance of AMH in fertility regulation and management underscores the importance of adopting a holistic approach to reproductive health. Through proper nutrition, adopting a healthy lifestyle, and getting appropriate advice, people can significantly increase the probability of successful pregnancy.
(Article Courtesy: Dr. Kshitiz Murdia, CEO & Co-Founder, Indira IVF)
Video
AMH levels are used as a measure of a woman’s fertility potential, especially in advancing age. Increased levels might indicate syndromes such as polycystic ovary syndrome (PCOS), whereas reduced levels normally show a lack of ovarian reserve. Such reduction in AMH creates an issue for conception, particularly at the older age, suggesting decreased fertility. Women with low AMH will more likely need higher doses of medicine to stimulate egg growth and may not respond as well to fertility treatments by IVF.
Low AMH levels, as actress Rubina Dilaik highlighted in her recent podcast, can pose hurdles to natural conception. Lower AMH levels reflect a decreased ovarian reserve, which means that there are fewer eggs available for fertilisation, and natural conception becomes difficult, especially in women with values less than 1.5. Additionally, those with levels of 1.5 to 4.5 usually have a normal reserve, while higher levels of 4.5 or more may indicate polycystic ovary syndrome (PCOS).
Low AMH levels in women aged 20-25 may lead to conception through natural means with quite minimal fertility evaluations or medical interventions required. Low AMH levels in women aged 35 and above constitute a serious issue as they often struggle to get pregnant naturally and the baby is at greater risk of chromosomal abnormalities. Research reflects a significant drop in the viable eggs in women above the age of 35.
Monitoring of AMH levels in regular blood tests at particular intervals within the menstrual cycle is a fundamental tool in detecting low ovarian reserves at an early stage, providing valuable information for family planning considerations. Acknowledging the significance of AMH in fertility regulation and management underscores the importance of adopting a holistic approach to reproductive health. Through proper nutrition, adopting a healthy lifestyle, and getting appropriate advice, people can significantly increase the probability of successful pregnancy.
(Article Courtesy: Dr. Kshitiz Murdia, CEO & Co-Founder, Indira IVF)
Video
